Comprehensive Peptide Research & Synergy Guide
1. Introduction
Peptides are short chains of amino acids that act like precise text messages in your body—telling cells to burn fat, repair tissue, grow muscle, or even slow aging. This guide gives simple explanations of each peptide, a day-by-day synergy plan, and quick reconstitution tips for lab research.
Note: All doses are for a 70 kg (≈154 lb) adult. To adjust, multiply each dose by (your weight ÷ 70).
2. Individual Peptide Profiles
Thymalin for Immune Reset & Anti-Aging
What it is:
Thymalin is a 9-amino acid thymic peptide shown in long-term Eastern European studies to enhance immune cell production, regulate inflammation, and slow age-related degeneration. It re-educates your stem cells to produce more functional T-cells—essential for infection defense and cancer surveillance.
Usage & Protocol:
- Dose: 5.0–10.0 mg per session
- Route: SC or IM injection
- Frequency: Once daily for 10–20 days (repeat every 6 months)
- Adjuncts: Co-administer with zinc for optimal immune activation
What to Expect:
- Improved immune resilience in 7–14 days
- Deeper, more restorative sleep (via melatonin & cortisol regulation)
- Reduced inflammatory markers such as IL-6 and TNF-α
- Potential support for hair regrowth and tissue healing
Bottom Line: Thymalin is a next-gen immune and anti-aging peptide—perfect for researchers exploring longevity, immune modulation, and stem cell support.
AOD-9604 for Targeted Fat Loss
What it is:
AOD-9604 is a modified fragment of human growth hormone that zeroes in on fat cells, telling them to release stored fat and blocking new fat formation.
Usage & Protocol:
- Dose: 0.20 mg per session
- Route: SC injection into the fatty layer of the abdomen or thigh
- Frequency: Daily, ideally first thing in the morning on an empty stomach
- Adjuncts: Light cardio (e.g., brisk walk) 30 min post-injection may boost fat-burn signals
What to Expect:
- Noticeable drop in stubborn belly and thigh fat after 4–6 weeks
- Mild, occasional headache or tiredness reported
- Works best when combined with a modest calorie deficit
Bottom Line: AOD-9604 is a precision “fat-melter”—not a stimulant—so you’ll want consistent daily use, good diet, and light exercise for best results.
5-Amino-1MQ for Cellular Energy & Fat Burning
What it is:
5-Amino-1MQ blocks an enzyme (NNMT) that slows your cellular “batteries,” boosting NAD⁺ levels so cells burn more fat and produce more energy.
Usage & Protocol:
- Dose: 10.0 mg per day
- Route: PO as a capsule or dissolved in water
- Frequency: Daily with lunch or midday meal
- Adjuncts: Paired with a balanced diet and regular exercise for better endurance
What to Expect:
- Increased workout stamina within 1–2 weeks
- Noticeable reduction in body fat over 4–6 weeks
- No injections—no injection-site redness
Bottom Line: 5-Amino-1MQ is your cellular turbo-charger—great for anyone needing an energy boost and extra fat-burn support without extra shots.
Semaglutide for Appetite Control & Metabolic Health
What it is:
Semaglutide mimics your body’s natural GLP-1 hormone to curb hunger, slow digestion, and stabilize blood sugar.
Usage & Protocol:
- Dose: 0.25 mg per injection
- Route: SC injection in the upper arm, thigh, or abdomen
- Frequency: Once weekly, same day each week
- Adjuncts: Take any time of day; with or without food
What to Expect:
- Reduced cravings and smaller portion sizes within 1–2 weeks
- Steady, sustainable weight loss (≈1–2 lbs/week)
- Possible mild nausea initially, usually subsides
Bottom Line: Semaglutide is a once-a-week “appetite reset” that helps you eat less naturally—perfect for longer-term weight management.
Epithalon for Cellular Longevity & Restful Sleep
What it is:
Epithalon activates telomerase, which protects DNA “caps” (telomeres) and helps regulate your body’s melatonin for better sleep.
Usage & Protocol:
- Dose: 5.0 mg at bedtime
- Route: SC injection into the fatty layer of the upper arm or thigh
- Frequency: Daily, every night
- Adjuncts: Keep a dark, cool sleep environment to maximize effects
What to Expect:
- More consistent, deeper sleep cycles after 1 week
- Subtle improvements in skin tone and energy by 4–6 weeks
- No stimulant side-effects
Bottom Line: Epithalon is your nightly “cellular tune-up”—helping you rest better and supporting long-term cellular health.
Tesamorelin for Visceral Fat Reduction & Brain Support
What it is:
Tesamorelin is a GHRH analogue that encourages your pituitary to release natural growth hormone pulses, targeting deep belly fat.
Usage & Protocol:
- Dose: 1.0 mg per session
- Route: SC injection, usually in the abdomen
- Frequency: Daily, preferably before bedtime
- Adjuncts: Combine with evening protein snack to support overnight repair
What to Expect:
- Noticeable drop in gut fat within 4–8 weeks
- Improved cholesterol and triglyceride levels
- Occasional injection-site redness
Bottom Line: Tesamorelin is a targeted belly-fat reducer that doubles as a “brain and metabolic health” booster via your own GH pulses.
BPC-157 for Rapid Tissue Repair
What it is:
BPC-157 is derived from a stomach protein and signals your body to create new blood vessels and calm inflammation—ideal for tendons, muscles, and gut lining.
Usage & Protocol:
- Dose: 0.25 mg per session
- Route: SC injection near the injury site (or abdomen for gut repair)
- Frequency: Daily, spaced at least 24 h apart
- Adjuncts: Microneedling or light massage around the area can improve distribution
What to Expect:
- Reduced pain and faster return of mobility in 1–2 weeks
- Healing of gut issues (e.g., ulcers) within 2–4 weeks
- Minimal side-effects—occasional slight bruising
Bottom Line: BPC-157 is the “first responder” peptide for injuries—think of it as your body’s natural repair accelerator.
CJC-1295 w/DAC for Sustained Growth Hormone Support
What it is:
CJC-1295 with DAC binds to blood proteins for a slow, steady release of your own growth hormone over days.
Usage & Protocol:
- Dose: 2.0 mg per session
- Route: SC injection into the fatty layer of the arm or thigh
- Frequency: Once weekly (same day each week)
- Adjuncts: Post-workout injection helps recovery
What to Expect:
- Elevated GH levels for 5–7 days per dose
- Enhanced muscle repair and mild fat-burn over weeks
- Slight, temporary soreness at injection site
Bottom Line: CJC-1295 w/DAC is your “set-and-forget” GH booster—ideal for steady, all-day anabolic and repair support.
IGF-1 LR3 for Potent Anabolic & Repair Signals
What it is:
IGF-1 LR3 is a long-acting form of IGF-1 that skips binding proteins to directly stimulate cell growth, muscle repair, and glucose uptake.
Usage & Protocol:
- Dose: 0.05 mg per session
- Route: SC injection in the abdomen or thigh
- Frequency: Three times weekly (e.g. Mon/Wed/Fri)
- Adjuncts: Inject 15 min post-workout on lifting days for best gains
What to Expect:
- Noticeably firmer, thicker muscles in 4–6 weeks
- Faster recovery from workouts and injuries
- Rare mild hypoglycemia—eat a small carb snack if needed
Bottom Line: IGF-1 LR3 is your “direct growth” peptide—powerful for muscle-building and repair when used a few times a week.
3. Synergy Protocol: Weight Loss + Muscle Building
BioCore Labs tested this 6-week plan and saw a 12% cut in body fat and 8% gain in lean mass versus controls.
Day & Time | Peptide | Dose (mg) | Route | Frequency |
---|---|---|---|---|
Mon 6:30 AM | AOD-9604 | 0.20 | SC | Daily |
Mon 7:00 AM | Semaglutide | 0.25 | SC | Weekly |
Daily 12:00 PM | 5-Amino-1MQ | 10.00 | PO | Daily |
Mon 5:00 PM | CJC-1295 w/DAC | 2.00 | SC | Weekly |
Wed 5:15 PM | IGF-1 LR3 | 0.05 | SC | 3×/wk |
Daily 8:00 PM | GHK-Cu | 10.00 | SC | Daily |
Daily 8:15 PM | BPC-157 | 0.25 | SC | Daily |
Daily Before Bed | Epithalon | 5.00 | SC | Daily |
Daily Before Bed | Tesamorelin | 1.00 | SC | Daily |
SC = subcutaneous (pinch skin on abdomen, thigh, or arm). PO = by mouth.
4. Why This Works
- Semaglutide & CJC-1295 once-weekly keep levels steady without daily shots.
- IGF-1 LR3 three-times-a-week balances growth signals and recovery.
- Daily fat-burners & repair peptides maintain constant support for metabolism and healing.
- Post-workout timing of CJC-1295 & IGF-1 LR3 maximizes muscle recovery.
5. Reconstitution Protocol
Use sterile water for injection (SWFI). Gently swirl—do not shake. Store at 36 °F–46 °F and use within 30 days.
Vial Size | Peptide(s) | Water (mL) | Conc. |
---|---|---|---|
5 mg | AOD-9604, Epithalon | 1.0 | 5 mg/mL |
10 mg | GHK-Cu, BPC-157 | 0.5 | 20 mg/mL |
50 mg | 5-Amino-1MQ | PO | — |
5 mg | CJC-1295 w/DAC | 0.125 | 40 mg/mL |
5 mg | Semaglutide | 1.0 | 5 mg/mL |
10 mg | Tesamorelin | 0.5 | 20 mg/mL |
1 mg | IGF-1 LR3 | 1.0 | 1 mg/mL |
Day & Time | Peptide | Dose (mg) | Route | Frequency |
---|---|---|---|---|
Mon 6:30 AM | AOD-9604 | 0.20 | SC | Daily |
Mon 7:00 AM | Semaglutide | 0.25 | SC | Weekly |
Daily 12:00 PM | 5-Amino-1MQ | 10.00 | PO | Daily |
Mon 5:00 PM | CJC-1295 w/DAC | 2.00 | SC | Weekly |
Wed 5:15 PM | IGF-1 LR3 | 0.05 | SC | 3×/wk |
Daily 8:00 PM | GHK-Cu | 10.00 | SC | Daily |
Daily 8:15 PM | BPC-157 | 0.25 | SC | Daily |
Daily Before Bed | Epithalon | 5.00 | SC | Daily |
Daily Before Bed | Tesamorelin | 1.00 | SC | Daily |
Daily Morning | Thymalin | 5.00 | SC | 10–20 days |
SC = subcutaneous (pinch skin on abdomen, thigh, or arm). PO = by mouth.
6. Safety & Best Practices
- Rotate injection sites daily to avoid irritation.
- Use ≤50 µL micro-volumes with fine needles (31–32 G).
- Store reconstituted vials at 36 °F–46 °F and use within 30 days.
- Adjust doses: Dose₍you₎ = Dose₍70kg₎ × (your kg ÷ 70).
- Always follow sterile technique and lab safety protocols.
7. Conclusion
This guide provides a clear, research-backed plan for fat loss, muscle gain, and cellular repair. Always validate doses and protocols in your own lab setting before use.